Publications

Implications of the Network Theory for the Treatment of Mental Disorders: A Secondary Analysis of a Randomized Clinical Trial

The effects of psychotherapy can also be explained with Network Theory: in the course of effective psychotherapy, the strength of interaction between depressive symptoms decreases, e.g. psychomotor retardation is less likely to be associated with suicidal ideation. Or in less technical language: when you are treated with effective psychotherapy, feelings of inertia are less likely […]

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Neural correlates of affective task switching and asymmetric affective task switching costs

New Study: Investigating the neural correlates of affective task switching and asymmetric affective task switching costs. Read the full article for more information: Eckart, C., Kraft, D., Rademacher, L., & Fiebach, C. J. (2023). Neural correlates of affective task switching and asymmetric affective task switching costs. Social cognitive and affective neuroscience, 18(1), nsac054. https://doi.org/10.1093/scan/nsac054

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The non-specific nature of mental health and structural brain outcomes following childhood trauma

New Study: Childhood trauma as a transdiagnostic risk factor for mental health disorders. Explore how patterns of trauma influence psychopathology and brain structure. Read more about the findings and their implications in our latest research article. More information you can find here: Haidl, Borgwardt, S., … Koutsouleris, N. (2023). The non-specific nature of mental health

The non-specific nature of mental health and structural brain outcomes following childhood trauma Read More »

Negative symptoms, striatal dopamine and model-free reward decision-making in schizophrenia

New Study: Investigating the underlying mechanisms of negative symptoms in patients with schizophrenia. Gain insights into the impaired reward prediction influence, dopamine alterations, and executive dysfunction that contribute to these debilitating symptoms. Read the full article here. Brandl, F., …, Avram, M., …, Sorg, C. (2023). Negative symptoms, striatal dopamine and model-free reward decision-making in

Negative symptoms, striatal dopamine and model-free reward decision-making in schizophrenia Read More »

The Effectiveness of Metacognitive Therapy Compared to Behavioral Activation for Severely Depressed Outpatients: A Single-Center Randomized Trial

Major depressive disorder (MDD) is a highly prevalent and disabling disorder. This study examines two psychotherapy methods for MDD, behavioral activation (BA), and metacognitive therapy (MCT), when applied as outpatient treatments to severely affected patients. More information you can find here: Schaich, A., …, Klein, J. P., & Fassbinder, E. (2023). The Effectiveness of Metacognitive

The Effectiveness of Metacognitive Therapy Compared to Behavioral Activation for Severely Depressed Outpatients: A Single-Center Randomized Trial Read More »

Psychedelics in Psychiatry – Development and Current State in Germany

Clinical research on the therapeutic efficacy of psychedelics is currently experiencing a renaissance. Available scientific evidence on their efficacy in various psychiatric conditions, as well as their legally approved use in some countries of the world, show the possibility of their future application in clinical practice also in Germany. The field is facing substantial challenges

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Low Self-Esteem and Music Performance Anxiety Can Predict Depression in Musicians

Abstract Background: Music performance anxiety (MPA) is an issue concerning musicians from all levels but is still a rather neglected topic in the education and employment of musicians. This study investigated the link between self-esteem, MPA, and depression within a German-speaking sample of musicians of different professions. The underlying question of this study was generated during

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Disrupted subcortical functional connectome gradient in drug-naïve first-episode schizophrenia and the normalization effects after antipsychotic treatment

Abstract Antipsychotics are thought to improve schizophrenia symptoms through the antagonism of dopamine D2 receptors, which are abundant mainly in subcortical regions. By introducing functional gradient, a novel approach to identify hierarchy alterations by capturing the similarity of whole brain fucntional connectivity (FC) profiles between two voxels, the present study aimed to characterize how the

Disrupted subcortical functional connectome gradient in drug-naïve first-episode schizophrenia and the normalization effects after antipsychotic treatment Read More »

Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium

Abstract Schizophrenia (SZ) is associated with an increased risk of life-long cognitive impairments, age-related chronic disease, and premature mortality. We investigated evidence for advanced brain ageing in adult SZ patients, and whether this was associated with clinical characteristics in a prospective meta-analytic study conducted by the ENIGMA Schizophrenia Working Group. The study included data from

Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium Read More »

How do we arrive at our beliefs “Neurocomputational mechanisms of affected beliefs” out now!

Affected beliefs Researchers at Lübeck University show links between emotions and the formation of self-efficacy beliefs Why do some people believe that they are good at something and others not, while performing exactly similar? A recent study from Lübeck University, Germany, finds that emotional experiences are linked to the way people establish novel beliefs about

How do we arrive at our beliefs “Neurocomputational mechanisms of affected beliefs” out now! Read More »

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